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Septerna Inc (SEPN) Stock Grade

SEPN · Healthcare

B-
Grade updated: September 29, 2026
Computed by the GradeMyInvestments scoring model from revenue growth, profitability, balance-sheet strength, and analyst targets.
Market Cap
$1.8B
P/E Ratio
—
Revenue Growth (YoY)
+4174.5%
Net Margin
-106.4%
Return on Equity
—
Dividend Yield
None

About Septerna Inc's fundamentals

Septerna is a biotechnology company with a market capitalization of $1.8 billion that reported extraordinary revenue growth of 4,174.5% year-over-year, indicating a significant commercial scaling of its business. However, the company currently operates at a loss with a net margin of -106.4% and reported a net loss in its latest annual statement. Despite the accounting losses, Septerna generated positive free cash flow, suggesting the company is converting revenue into actual cash despite not yet achieving profitability. The company does not pay a dividend.

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