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Karyopharm Therapeutics Inc. (KPTI) Stock Grade

KPTI · Healthcare

C
Grade updated: September 29, 2026
Computed by the GradeMyInvestments scoring model from revenue growth, profitability, balance-sheet strength, and analyst targets.
Market Cap
$36.7M
P/E Ratio
—
Revenue Growth (YoY)
+0.6%
Net Margin
-134.2%
Return on Equity
66.9%
Dividend Yield
None

About Karyopharm Therapeutics Inc.'s fundamentals

Karyopharm Therapeutics is a small-cap biotechnology company with a market capitalization of $36.7 million that reported minimal revenue growth of 0.6% year-over-year and a substantial net loss reflected in its negative net margin of -134.2%. The company does not currently pay a dividend and lacks a meaningful price-to-earnings ratio due to its unprofitability. Despite the operating losses, the company reported a return on equity of 66.9%, which may reflect volatility in shareholder equity rather than operational strength given the net loss position.

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